biofilms | CMAC

biofilms

Biofilm formation of clinical isolates of opportunistic microorganisms under the influence of disinfectants

Objective. To assess the ability of clinical isolates of opportunistic microorganisms to accumulate biofilm biomass under the influence of composite disinfectants. Materials and Methods. The study included 53 strains (49 – K. pneumoniae, 4 – P. aeruginosa) obtained from two multidisciplinary children’s hospitals at the city and regional levels. Specimens were collected from different loci of patients, medical devices, and environmental objects. To assess the reaction of biofilms (BF) of clinical isolates to the effects of disinfectants (DIs), three composite DIs were used: No.

Effects of bacteriophages on biofilms formed by Staphylococcus aureus isolated from patients with orthopedic infection

Objective. To study effects of bacteriophages on biofilm formation and formed biofilm by S. aureus isolated from patients with orthopedic infection. Materials and Methods. A total of 50 clinical strains of S. aureus were tested. Species identification was performed by MALDI-TOF MS, antibiotic susceptibility – in accordance with the EUCAST v21. Isolates susceptibility to bacteriophages «Sextafag» (Microgen, Russia) was determined by MPA medium. The antibacterial activity of phages against S.

Unresolved issues of antibiotic therapy of infections caused by Staphylococcus aureus

Staphylococcal infections are widespread among outpatients and hospitalized patients. Despite the apparent diversity of the “menu” of anti-staphylococcal drugs, treatment results in several patients are not good as expected. This is due to the …

Matrix of Microbial Biofilms

This literature review was aimed to summarize information on an extracellular matrix, which is one of the most important components of microbial biofilms. Structural and biochemical characteristics of biofilms matrix produced by the most common …