biofilms

Effects of bacteriophages on biofilms formed by Staphylococcus aureus isolated from patients with orthopedic infection

Objective. To study effects of bacteriophages on biofilm formation and formed biofilm by S. aureus isolated from patients with orthopedic infection. Materials and Methods. A total of 50 clinical strains of S. aureus were tested. Species identification was performed by MALDI-TOF MS, antibiotic susceptibility – in accordance with the EUCAST v21. Isolates susceptibility to bacteriophages «Sextafag» (Microgen, Russia) was determined by MPA medium. The antibacterial activity of phages against S.

Unresolved issues of antibiotic therapy of infections caused by Staphylococcus aureus

Staphylococcal infections are widespread among outpatients and hospitalized patients. Despite the apparent diversity of the “menu” of anti-staphylococcal drugs, treatment results in several patients are not good as expected. This is due to the …

Matrix of Microbial Biofilms

This literature review was aimed to summarize information on an extracellular matrix, which is one of the most important components of microbial biofilms. Structural and biochemical characteristics of biofilms matrix produced by the most common …