Pilot Study of LongSterm Azithromycin Prophylaxis of Acute Bacterial Infections of Respiratory Tract in Military Persons

Objective. Introduction Azithromycinis anazalide with high activity against most frequent pathogens causing respiratory community-acquired infections – Streptococ cus spp., Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, – an d long tissue concentrations. These features make it very attractive for use inprophylaxis of bacterial respiratory tract infections. The objective of this study was to determine azithromycin ability to prevent respiratory tract infection during winter period among military recruits. Materials and Methods. Two groups of military recruits (100 males in each group) were entered the same training center near Moscow in January 1999.