antimycotics

Clinical pharmacology and practical aspects of isavuconazole use

The steadily increasing incidence of invasive fungal infections, influenced to some extent by the COVID-19 pandemic, caused by both yeast and molds makes it necessary to improve the antifungal therapies used. Historically, azoles have held a key …

Promising antimycotics for the treatment of invasive infections

This paper provides a review of the largest studies (over the period of 2018 to 2023) of promising novel antimycotics and their possible role in the treatment of invasive mycoses, including infections caused by resistant Candida and Aspergillus …

The New Approach to the Topical Therapy of Onychomycoses

Onychomycosis is a fungal infection of nails of fingers of the hands or feet, resulting in thinning, and the subsequent destruction, discoloration and desquamation of the nail plate from the nail bed. The etiology of onychomycosis in most cases are …

Empiric Therapy of Invasive Candidiasis in Intensive Care Units: Current State of Problem

The high prevalence of invasive candidiasis (IC) in intensive care units (ICU) is one of the major problems of medical mycology and the modern medicine in general. More than 10% of all infections in ICU are caused by Candida spp. Infections caused by …

Analysis of Antifungal Agents Consumption in Large Clinic

Retrospective study of antifungal consumption in 1029-bed hospital during the 2004–2006 was performed. Defined daily dose (DDD) per 100 bed-days was calculated to determine consumption of antifungal agents. ABC analysis was used to determine …

Current Options for the Pharmacotherapy of the Invasive Candidiasis in Children

Invasive mycoses are the substantial cause of morbidity and mortality in immunocompromised children. The prevalence of invasive mycoses in this population is around 25% and the mortality rates are run up to 55-60%. Invasive candidiasis is a major …

Systemic Antimycotics: Key Aspects and Perspectives

Invasive fungal infections are still a growing problem of modern medicine. The prevalence of invasive fungal infections significantly increased during the last few decades concurrently with the increasing number of immunocompromised patients. The …

Management of Patients with Candidiasis: Overview of New IDSA Guidelines

Сandidiasis remains the most frequently occurred form of invasive fungal infections and represents the major part of superficial mycoses. Important factor that contribute to create an accurate guidelines is the increasing number of candidiasis …