Clinical Microbiology and Antimicrobial Chemotherapy. 2025; 27(3):406-416
Objective. Determination of the antimycobacterial efficacy of a composite material impregnated with silver in relation to M. tuberculosis.
Materials and Methods. Samples of the outer shell of bulk porous composite materials with antimycobacterial substances included in the structure (silver (Ag) nanoparticles, as well as silver proteinate) were obtained at the Kurchatov Institute. In total, two types of samples with different particle contents were obtained: chitosan Ag and chitosan Ag2. To obtain an outer shell with an impregnated silver proteinate complex from chitosan Primex 43040 with glutaraldehyde: an aqueous solution of silver proteinate with different concentrations («chitosan Pr» and «chitosan Pr2») was added.