antifungal therapy

Combination of invasive aspergillosis and mucormycosis in children: a case report and the results of a multicenter study

Objective. To study risk factors, etiology, clinical signs and treatment outcomes of invasive aspergillosis (IA) and mucormycosis combination (IAM) in children. Materials and Methods. A retrospective review of Saint-Petersburg register (1998–2021) of patients with IA was done and children with IAM were included. EORTC/MSGERG 2019 criteria were used for diagnosing and treatment results evaluation of invasive mycosis. We presented a clinical case of IAM in a child with acute lymphoblastic leukemia relapse.

Systemic Antimycotics: Key Aspects and Perspectives

Invasive fungal infections are still a growing problem of modern medicine. The prevalence of invasive fungal infections significantly increased during the last few decades concurrently with the increasing number of immunocompromised patients. The …

Pharmacotherapy of Vulvovaginal Candidiasis According to Pharmacoepidemiology Data and Evidence-Based Medicine

Approximately 75% of women experience at least one episode of acute vulvovaginal candidiasis during their life. In the 1980-90s, almost two-fold increase in fungal vaginitis was observed with increase in number of cases caused by non-albicans strains …

Management of Patients with Candidiasis: Overview of New IDSA Guidelines

Сandidiasis remains the most frequently occurred form of invasive fungal infections and represents the major part of superficial mycoses. Important factor that contribute to create an accurate guidelines is the increasing number of candidiasis …

New Drugs for the Treatment of Invasive Mycoses

Invasive mycoses becoming more and more important problem of the modern medicine that is reflecting the increasing number of immunocompromised patients population. Despite the fact that the main causative agents remain Candida albicans, Aspergillus …

Criteria Used When Initiating Antifungal Therapy Against Candida spp. in the Intensive Care Unit

Translated and reprinted with permission from «International Journal of Antimicrobial Agents» 2000; 15:83-90.

Invasive candidiasis is a life threatening complication for intensive care unit (ICU) patients. The infection is difficult to …