antibiotic therapy

Antimicrobial resistance and antimicrobial therapy modification during COVID19 pandemic in large tertiary hospital

Objective. assessment of the evolution of the microbiological landscape of the hospital for the period of operation in 2020 into a pandemic of a new coronavirus infection in various departments, including intensive care units; change depending on the results of antibacterial therapy regimens. Materials and Methods. In a retrospective study, conducted from June to December 2020, in a multidisciplinary hospital working with COVID-19 infection, the resistance of isolated strains of microorganisms was analyzed in patients of different age groups.

Unresolved issues of antibiotic therapy of infections caused by Staphylococcus aureus

Staphylococcal infections are widespread among outpatients and hospitalized patients. Despite the apparent diversity of the “menu” of anti-staphylococcal drugs, treatment results in several patients are not good as expected. This is due to the …

Diagnosis treatment and prophylaxis of community-acquired bacterial meningitis: the review of the guidelines of European Society for Clinical Microbiology and Infectious Diseases

Community-acquired bacterial meningitis is one of the most serious infectious lesions of the central nervous system that can quickly lead to death in even previously healthy patients with inadequate treatment. The article provides an overview of the …

Current Approaches to Diagnosis and Treatment of Respiratory Tract Infections in Patients with Cystic Fibrosis

Chronic airway inflammation and infection are the main cause of mortality in patients with cystic fibrosis (CF), therefore effective antimicrobial therapy is important part of treatment of CF-lung disease. In the article, an overview on present …

Local Antimicrobial Resistance Profile as a Basis for the Choice of Antimicrobial Therapy of Staphylococcal Prosthetic Joint Infections

Objective. To determine the most effective antibiotics for therapy of infectious complications of prosthetic joint implantation caused by S. aureus and S. epidermidis. Materials and Methods. The antibiotic resistance profiles were determined for 535 clinical S. aureus and 211 S. epidermidis isolates. All the strains were isolated from the removed prosthesis and biological samples from patients with prosthetic joint infection (PJI). Susceptibility of clinical isolates was determined to 14 antibiotics according to EUCAST guidelines.

Analysis of Antiviral and Antibacterial Therapy in Patients with Influenza A/H1N1 and Pneumonia

Analyzing the cases of treatment of pneumonia with influenza A/H1N1 in the background, it was noted that the outpatient antiviral therapy was provided mainly by «Arbidol». Neuraminidase inhibitors (Oseltamivir and Zanamivir) were used very …