antibacterial therapy

Potential for the use of macrolides in the antimicrobial therapy of severe community-acquired pneumonia in adults

This paper presents mechanism of action and antimicrobial spectrum of macrolides as well as the known acquired resistance mechanisms in the common pathogens causing community-acquired pneumonia, such as Streptococcus pneumoniae and Mycoplasma …

Antibiotics and community-acquired lower respiratory tract infections. To whom? Which one?

This paper discusses an etiology, patient characteristics, and antimicrobial resistance surveillance data, as well as other factors which help to determine indications for administration and choice of antibiotics for the treatment of patients with …

Infectious endocarditis caused by Gemella haemolysans: clinical issues and treatment approaches

Gemella haemolysans is a commensal of the human oral cavity, upper respiratory tract, and gastrointestinal tract, which in some cases can cause serious infections, including infective endocarditis (IE). IE caused by G. haemolysans is more common in …

Bacterial infections in patients with liver cirrhosis

Patients with liver cirrhosis are at substantial risk of bacterial infections. Bacterial complications account for more than 30% of hospitalizations and contribute significantly to mortality among cirrhotic patients. The most common bacterial …

A review of the Infectious Diseases Society of America (IDSA) guidelines on the diagnosis and treatment of spondylitis in adults

Spondylitis is a common disease in general clinical practice, which can be associated with a serious risk of adverse outcomes and severe disabling effects in case of late diagnosis and inadequate management of the patient. This article provides an …

Study to assess incidence of acute otitis media in children under 5 years of age in Russia (PAPIRUS-AOM)

At this prospective 12-months study we investigated the incidence of acute otitis media (AOM), it’s severity and frequency of hospitalization in children from 0 to 5 years old. We detected, that AOM-burden in children under 5-years old in the …

Antibacterial Therapy Is a Main Reason for Professional Contacts to Clinical Pharmacologists in Tyumen Hospitals

An anonymous questioning of different clinical specialists in Tyumen hospitals was performed to assess their satisfaction with professional contacts with clinical pharmacologists. Results of the questioning indicate the following: clinical …

Comparative Clinical and Microbiological Efficacy of 7-day and 10-day Courses of New Formulation of Josamycin in the Treatment of Acute Streptococcal Tonsillopharyngitis in Children and Adolescents

This article presents data of multicenter open-label randomized clinical trial of clinical and microbiological efficacy and safety of 7- and 10-day courses of new formulation («Solutab») of josamycin in the treatment of acute streptococcal …

Efficacy of Intervention Campaign in Outpatients with Acute Tonsillopharyngitis in Smolensk

In this paper the main results of intervention campaign carried out among physicians and patients in different outpatient settings of Smolensk region are presented and discussed. The campaign aimed to improve the practice of antibacterial therapy in …

Patterns of Antibacterial Therapy of Community-Acquired Pneumonia in Hospitalized Adults in Different Regions of Russia: Lessons from Multicentre Pharmacoepidemiology Study

The aim of the study was to examine the patterns of systemic antibiotic (AB) use in adults with communityacquired pneumonia (CAP) in multi-word hospitals of different regions of Russia and assess the adherence of antibacterial therapy to the Russian …