antibacterial therapy

COVID19 pandemic is a «pandemic» of antimicrobial therapy

The article presents a critical analysis of antibiotic usage tactics in the treatment of patients with COVID-19 existing in Russian and foreign healthcare, and discusses the possible causes of unjustified antibiotic aggression in this category of …

Biomarkers of infection in the optimization of antibacterial therapy: justified expectations

Despite the continuous improvement of approaches to antimicrobial therapy and the emergence of new highly effective antibiotics, severe bacterial infections being a significant cause of morbidity and mortality remain a top of mind issue for …

Potential for the use of macrolides in the antimicrobial therapy of severe community-acquired pneumonia in adults

This paper presents mechanism of action and antimicrobial spectrum of macrolides as well as the known acquired resistance mechanisms in the common pathogens causing community-acquired pneumonia, such as Streptococcus pneumoniae and Mycoplasma …

Antibiotics and community-acquired lower respiratory tract infections. To whom? Which one?

This paper discusses an etiology, patient characteristics, and antimicrobial resistance surveillance data, as well as other factors which help to determine indications for administration and choice of antibiotics for the treatment of patients with …

Infectious endocarditis caused by Gemella haemolysans: clinical issues and treatment approaches

Gemella haemolysans is a commensal of the human oral cavity, upper respiratory tract, and gastrointestinal tract, which in some cases can cause serious infections, including infective endocarditis (IE). IE caused by G. haemolysans is more common in …

Bacterial infections in patients with liver cirrhosis

Patients with liver cirrhosis are at substantial risk of bacterial infections. Bacterial complications account for more than 30% of hospitalizations and contribute significantly to mortality among cirrhotic patients. The most common bacterial …

A review of the Infectious Diseases Society of America (IDSA) guidelines on the diagnosis and treatment of spondylitis in adults

Spondylitis is a common disease in general clinical practice, which can be associated with a serious risk of adverse outcomes and severe disabling effects in case of late diagnosis and inadequate management of the patient. This article provides an …

Study to assess incidence of acute otitis media in children under 5 years of age in Russia (PAPIRUS-AOM)

At this prospective 12-months study we investigated the incidence of acute otitis media (AOM), it’s severity and frequency of hospitalization in children from 0 to 5 years old. We detected, that AOM-burden in children under 5-years old in the …

Antibacterial Therapy Is a Main Reason for Professional Contacts to Clinical Pharmacologists in Tyumen Hospitals

An anonymous questioning of different clinical specialists in Tyumen hospitals was performed to assess their satisfaction with professional contacts with clinical pharmacologists. Results of the questioning indicate the following: clinical …

Comparative Clinical and Microbiological Efficacy of 7-day and 10-day Courses of New Formulation of Josamycin in the Treatment of Acute Streptococcal Tonsillopharyngitis in Children and Adolescents

This article presents data of multicenter open-label randomized clinical trial of clinical and microbiological efficacy and safety of 7- and 10-day courses of new formulation («Solutab») of josamycin in the treatment of acute streptococcal …