antibacterial agents | CMAC

antibacterial agents

Regional distribution of antibiotic resistance in Bacteroides spp. and Clostridium perfringens strains isolated from coloproctological patients in the Russian Federation

Objective. To study susceptibility of clinical Bacteroides spp. and Clostridium perfringens isolates to antimicrobial agents across different regions of the Russian Federation and to identify regional patterns of antimicrobial resistance. Materials and Methods. The study included 1,685 isolates of obligate anaerobic bacteria belonging to 107 species, isolated from patients in 60 regions of the Russian Federation during period from January 2023 to December 2024. Among them, 144 C. perfringens isolates from 37 regions, and 370 Bacteroides spp.

Siderophore‑antibiotic conjugates: structural diversity and antibacterial activity

Due to uncontrolled growth of antimicrobial resistance, in the near future humanity may return to the «pre-antibiotic era» with no reliable antimicrobial therapy even for previously easily treatable infectious diseases. One of possible solutions is …

Hepatotoxicity of Antibacterial Agents in Clinical Practice

Antibacterial agents take a first place among causes of non-acetaminophen (paracetamol) associated druginduced liver injury (DILI) and fulminant liver failure in European countries and the US. The leading hepatotoxic antibiotic is …