Clinical Microbiology and Antimicrobial Chemotherapy. 2010; 12(2):163-169
In 2010 the world celebrates the 65th anniversary when the Nobel Prize in Physiology or Medicine was awarded to A. Fleming, H. Florey, and E.B. Chain «for the discovery of penicillin and its curative effect in various infectious diseases». Since then penicillin has saved infinitely many lives. The discovery of penicillin has become a strong impulse for the development of antimicrobial chemotherapy. Moreover, penicillin was the first drug that recognized a phenomenon such as resistance of microorganisms to antibiotics. However, penicillin is still an effective therapeutic agent in the treatment of several infections, such as tonsillopharyngitis, erysipelas, and syphilis.