Diseases and Pathogens | CMAC

Diseases and Pathogens

Biofilm formation by Candida spp. isolated from blood culture in patients with or without hematological malignancies

Objective. To evaluate the biofilm formation by isolates of Candida spp. obtained from blood culture in patients with or without hematological malignancies. Materials and Methods. Biofilm formation by Candida spp. was determined by the method of Pierce C. and Tumbarello M. Isolates with optical density (OD) >0.1 were considered as biofilm-forming. Results. A total of 109 isolates of Candida spp. (C. albicans [n=22], C. parapsilosis [n=22], C. tropicalis [n=22], C.

Biological characteristics and virulence of Helicobacter pylori

his review summarizes the most recent data on the biological characteristics of Helicobacter pylori (morphological, cultural, biochemical). H. pylori pathogenicity factors promoting colonization, adhesion, biofilm formation, aggression, and …

Vaccines for travel and vaccines for adults: moving targets!

This short review provides up-to-date information on vaccination problems for travelers and adults in general, including hepatitis B, meningococcal infection, rabies, yellow fever, measles. The article presents the general principles of approaches to …

Vaccination against pneumococcal infections in adults

The following key issues of pneumococcal infection prophylaxis were discussed during the expert council: incidence rates of community-acquired pneumococcal pneumonia and other pneumococcal infections, local epidemiological data, increases in …

Arcanobacterium haemolyticum: clinical significance, diagnosis, and antimicrobial therapy

Arcanobacterium haemolyticum is a causative agent of pharyngitis, skin and soft tissues infections, and can cause severe infections in patients with pneumonia, osteomyelitis, septicemia, and pneumothorax. It is a Gram-positive facultative anaerobic …

Prognostic rules for invasive candidiasis risk assessment in ICU patients

nvasive candidiasis is an extremely important problem for severe patients in intensive care units. The high rates of attributive mortality are associated not only with the severity of the patient’s condition, but also with a delayed therapy due to …

Bacterial infections in patients with liver cirrhosis

Patients with liver cirrhosis are at substantial risk of bacterial infections. Bacterial complications account for more than 30% of hospitalizations and contribute significantly to mortality among cirrhotic patients. The most common bacterial …

A current state of mycobacterioses

Mycobacterioses are caused by multiple opportunistic bacteria that are ubiquitous. The incidence rate of nontuberculosis mycobacterial infections (NTM) is rising due to an increased number of immunocompromised patients and advances in diagnosis. …

A prevalence of Clostridium difficile-associated diarrhea in hospitalized patients (results of a Russian prospective multicenter study)

Objective. The objective of the study was to evaluate the prevalence of Clostridium difficile-associated diarrhea (CDAD) among hospitalized patients with antibiotic-associated diarrhea (AAD) in general and by specific types of medical care and hospital units. Materials and Methods. A prospective, cross-sectional, non-interventional, multicenter study. The main inclusion criteria were: patient age of 18 years and over, hospital stay of at least 48 hours, current antibiotic therapy or antibiotic therapy within the previous 30 days, loose stools (Bristol stool types 5-7 and stool frequency ≥3 within ≤24 consecutive hours or exceeding normal for the patient), and signed informed consent form.

Epidemiology of S. pneumoniae serotypes in the Russian Federation

The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological …