Diseases and Pathogens | CMAC

Diseases and Pathogens

Arcanobacterium haemolyticum: clinical significance, diagnosis, and antimicrobial therapy

Arcanobacterium haemolyticum is a causative agent of pharyngitis, skin and soft tissues infections, and can cause severe infections in patients with pneumonia, osteomyelitis, septicemia, and pneumothorax. It is a Gram-positive facultative anaerobic …

Prognostic rules for invasive candidiasis risk assessment in ICU patients

nvasive candidiasis is an extremely important problem for severe patients in intensive care units. The high rates of attributive mortality are associated not only with the severity of the patient’s condition, but also with a delayed therapy due to …

Bacterial infections in patients with liver cirrhosis

Patients with liver cirrhosis are at substantial risk of bacterial infections. Bacterial complications account for more than 30% of hospitalizations and contribute significantly to mortality among cirrhotic patients. The most common bacterial …

A current state of mycobacterioses

Mycobacterioses are caused by multiple opportunistic bacteria that are ubiquitous. The incidence rate of nontuberculosis mycobacterial infections (NTM) is rising due to an increased number of immunocompromised patients and advances in diagnosis. …

A prevalence of Clostridium difficile-associated diarrhea in hospitalized patients (results of a Russian prospective multicenter study)

Objective. The objective of the study was to evaluate the prevalence of Clostridium difficile-associated diarrhea (CDAD) among hospitalized patients with antibiotic-associated diarrhea (AAD) in general and by specific types of medical care and hospital units. Materials and Methods. A prospective, cross-sectional, non-interventional, multicenter study. The main inclusion criteria were: patient age of 18 years and over, hospital stay of at least 48 hours, current antibiotic therapy or antibiotic therapy within the previous 30 days, loose stools (Bristol stool types 5-7 and stool frequency ≥3 within ≤24 consecutive hours or exceeding normal for the patient), and signed informed consent form.

Epidemiology of S. pneumoniae serotypes in the Russian Federation

The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological …

A review of the Infectious Diseases Society of America (IDSA) guidelines on the diagnosis and treatment of spondylitis in adults

Spondylitis is a common disease in general clinical practice, which can be associated with a serious risk of adverse outcomes and severe disabling effects in case of late diagnosis and inadequate management of the patient. This article provides an …

Study to assess incidence of acute otitis media in children under 5 years of age in Russia (PAPIRUS-AOM)

At this prospective 12-months study we investigated the incidence of acute otitis media (AOM), it’s severity and frequency of hospitalization in children from 0 to 5 years old. We detected, that AOM-burden in children under 5-years old in the …

Diagnosis treatment and prophylaxis of community-acquired bacterial meningitis: the review of the guidelines of European Society for Clinical Microbiology and Infectious Diseases

Community-acquired bacterial meningitis is one of the most serious infectious lesions of the central nervous system that can quickly lead to death in even previously healthy patients with inadequate treatment. The article provides an overview of the …

Review of the guidelines for the treatment and prevention of invasive candidiasis in newborns and children

nvasive infections caused by Candida species are the most common invasive fungal infections in children of different age groups. Premature neonates, especially newborns with low and extremely low birth-weight, have very high mortality rates, with the …