Diseases and Pathogens | CMAC

Diseases and Pathogens

Current Views on the Therapy of Enterococcal Endocarditis

The recent approaches to the treatment of endocarditis caused by Enterococcus spp., including strains that are resistant to conventional therapy, are discussed in the article. The possible ways of reduction of nephrotoxicity in elder patients and in …

Clinical Features and Course of Pneumocystis Pneumonia in Non-HIV Patients

As a result of the increase in the number of diseases and conditions that are leading to secondary immunodeficiency, the problem of severe opportunistic infections becoming more and more actual.In the present article authors have described and …

A Problem of Sarcoidosis Treatment: Cause for Discussion and Controlled Trials

This literature review presents approaches to the treatment of sarcoidosis, which are based on currently offered hypothesis of its pathogensis.These include: influence on granulomatous inflammation (corticosteroids, cytotoxic agents, anti-malaria …

Severe Acute Respiratory Syndrome: New Pieces of Puzzle

Severe acute respiratory syndrome (SARS) is a new highly contagious disease, which first appeared in Guandong province on the south of continental China and spread through 29 countries of Europe, Asia, North and South America, Africa and Australia. …

Yersinia enterocolitica and Related Microorganisms

This literature review is devoted to Yersinia enterocolitica and other enteropathogenic Yersinia spp. The main biochemical and biological patterns of Y. enterocolitica and Y. pseudotuberculosis are listed, with the description of virulence factors …

Microbiological Description of Bordetella pertussis and Laboratory Diagnosis of Whooping Cough

Whooping cough remains a significant problem worldwide, even in countries with high number of immunized people. However, a lack of sensitive, specific and reproducible diagnostics for this infection that would meet the needs of healthcare system …

Efficacy of Cefoperazone/sulbactam in the Therapy of Bacterial Sepsis: Results of a Multicentre Study «IRIS»

The objective of this prospective multicentre study was to evaluate the efficacy of cefoperazone/sulbactam for monotherapy of patients with bacterial sepsis in different wards of multifield hospitals in Russia. Overall, in 14 study centers 127 …

Typing of Listeria monocytogenes on the Basis of Polymorphism of Genes Encoding the Pathogenecity Factors

Polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLP) analysis revealed polymorphism of prfA and plcA genes, encoding the pathogenecity factors in strains of Listeria monocytogenes. Phylogenetic analysis confirmed the …

Chryseobacterium (Flavobacterium) spp.: Clinical Significance, Identification, Antimicrobial Susceptibility

Along with known human pathogens, such as Pseudomonas aeruginosa, Acinetobacter spp., Burkholderia spp., group of non-fermentative Gram-negative rods includes gender Chryseo4 bacterium (former Flavobacterium). Chryseo-bacteria are ubiquitous …

Severe Acute Respiratory Syndrome (SARS)

Severe acute respiratory syndrome (SARS) is a new infectious disease, which first appeared in November 2002 in Southern China and spread through 29 countries of Europe, Asia, North and South America, Africa and Australia. According to official …