Antimicrobials

Invasive mycoses becoming more and more important problem of the modern medicine that is reflecting the increasing number of immunocompromised patients population. Despite the fact that the main causative agents remain Candida albicans, Aspergillus …

Reprinted from «International Journal of Antimicrobial Agents» 2002; 20:313,9 – with permission from Elsevier. (The translation has not been rewieved by Elsevier prior to printing).

A number of studies have been carried out on the effect of several …

The present in vitro study of antimicrobial susceptibility of nosocomial Gram,negative pathogens to cefepime and other antimicrobials has been performed by the ROSNET study group in 28 medical institutions in Russia. The most active agent against …

This paper presents analysis of microbiological, clinical and pharmacoeconomic studies of carbapenems. Use of carbapenems during the last two decades was not associated with emergence of resistance to these agents among clinically significant human …

Moxifloxacin is a new broad spectrum 8-meth-oxiquinolon with high activity against both Gram(+) and Gram(–) microorganisms as well as against anaerobes and intracellular pathogens. It is also active against microorganisms that are resistant to other …

Medical equipments, instruments and hands of medical personnel serve as one of the most important vehicles for the transmission of nosocomial infections, and as a result of this, disinfection and sterilization are considered as a main part of any …

The combination of ceftazidime with an aminoglycoside is a commonly used standard for empiric therapy of febrile neutropenia. A lot of attention is paid to the development of effective monotherapy for the treatment of this condition. One of the most …

The widespread of multy-resistant Gram-positive pathogens, especially methicillin-resistant staphylococci made us to reconsider our attitude to such an «old» drug as fusidic acid and to draw attention to its usefulness in therapy of the …

Moxifloxacin – new broad spectrum 8-methoxyquinolon with high activity against Gram(+) and Gram(-) microorganisms as well as against anaerobes and intracellular pathogens. It is also active against microorganisms that are resistant to other classes …

Spread of multiresistant bacteria makes us to reconsider our attitude to some well-known old antimicrobials, including polymyxins – a class of polypeptide antibiotics that are active against many multiresistant gram-negative nosocomial pathogens – …