Механизмы резистентности Pseudomonas aeruginosa к антибиотикам и их регуляция

Клиническая Микробиология и Антимикробная Химиотерапия. 2017; 19(4):308-319

​ Чеботарь И.В., Бочарова Ю.А., Маянский Н.А.
Pseudomonas aeruginosa антибиотики резистентность бета-лактамазы проницаемость эффлюкс
Раздел
Антибиотикорезистентность
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2017; 19(4):308-319

Аннотация

Синегнойная палочка (Pseudomonas aeruginosa) является опасным оппортунистическим патогеном. Одно из самых отрицательных клинически значимых свойств P. aeruginosa связано со способностью быстро приобретать устойчивость к антимикробным препаратам. Данный обзор представляет собой анализ современной научной литературы о молекулярно-генетических механизмах резистентности P. aeruginosa к антибиотикам. Рассмотрены вопросы приобретения и регуляции антибиотикорезистентности. Знание механизмов и регуляции резистентности является важной теоретической базой для выбора оптимальной антибиотикотерапии и планирования противоэпидемических мероприятий при синегнойной инфекции.

Чеботарь Игорь Викторович

ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России, Москва, Россия

Бочарова Ю.А.

ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России, Москва, Россия

Маянский Николай Андреевич

ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России, Москва, Россия

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