Современные возможности терапии анаэробных инфекций

Клиническая Микробиология и Антимикробная Химиотерапия. 2006; 8(4):298-313

​ Галкин Д.В., Кречикова О.И., Сухорукова М.В., Дехнич А.В.
анаэробы антибиотикорезистентность антианаэробная терапия
Раздел
Болезни и возбудители
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2006; 8(4):298-313

Аннотация

В последнее время появляется всё больше публикаций о неэффективности эмпирической терапии анаэробных инфекций в связи с устойчивостью возбудителей к применяемому режиму антибактериальной терапии. В сложившейся ситуации важно иметь достоверные локальные данные о чувствительности клинически значимых анаэробов к современным антибактериальным препаратам. В статье рассматриваются основные характеристики анаэробных инфекций, тенденции резистентности анаэробов к применяемым классам антибиотиков, а также представлены предложения по формированию стратегии выбора антибактериальной терапии анаэробных инфекций на основании результатов исследования чувствительности наиболее распространенных анаэробов, выделенных в стационарах города Смоленска у пациентов с инфекциями различной локализации. Результаты локального исследования свидетельствуют, что в настоящее время карбапенемы (имипенем, меропенем, эртапенем), нитроимидазолы (метронидазол, орнидазол), ингибиторозащищённые бета-лактамы (амоксициллин/клавуланат, амоксициллин/сульбактам, цефоперазон/сульбактам) и фторхинолоны IV поколения (моксифлоксацин) являются препаратами выбора для эмпирической антибактериальной терапии анаэробных инфекций.

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