Современные представления об инфекции Clostridium difficile

Клиническая Микробиология и Антимикробная Химиотерапия. 2002; 4(3):200-232

​ Лобзин Ю.В., Захаренко С.М., Иванов Г.А.
С.difficile антибиотикоассоциированная диарея антибактериальная терапия C.difficile-ассоциированная диарея псевдомембранозный колит
Раздел
Болезни и возбудители
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2002; 4(3):200-232

Аннотация

Clostridium difficile является основным возбудителем нозокомиальной диареи, связанной с назначением антимикробных препаратов. Однако данной проблеме в нашей стране не уделяется достаточного внимания. В настоящем обзоре литературы рассмотрены вопросы эпидемиологии C.difficile-инфекции, особенности взаимодействия C.difficile с макроорганизмом и роль факторов патогенности. Описаны клинические формы C.difficile-ассоциированных болезней: от бессимптомного носительства до псевдомембранозного колита. Дана сравнительная характеристика методов диагностики инфекции C.difficile. Изложены основные современные принципы лечения манифестных форм инфекции. Большое внимание уделено вопросам специфической терапии и проведения мероприятий по восстановлению микробиоценоза кишечника.

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