Аннотация
Для определения эпидемиологической картины антибиотикорезистентности штаммов S.pneumoniae изучена чувствительность назофарингеальных изолятов пневмококков,выделенных у здоровых детей, посещающих дошкольные организованные коллективы городов Москвы, Смоленска и Ярцево. Частота выделения пневмококков составила 55,9%. В соответствии со значениями минимальной подавляющей концентрации (МПК) резистентность пневмококков составила:к пенициллину – 7,5% (все штаммы были с промежуточной устойчивостью), эритромицину – 4,6%, кларитромицину – 4,6%, ко-тримоксазолу – 53,4%. Чувствитльность к амоксициллину/клавуланату составила 100%. Резистентность к бета-лактамным антибиотикам в исследованных городах не является существенной проблемой. Чувствительность пневмококков к макролидам значительно варьирует в различных регионах, однако устойчивость к ним невысока. Высокая частота резистентности пневмококков к ко-тримоксазолу свидетельствует о необходимости ограничения его использования в амбулаторной практике.
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