ulcerative colitis

Objective. To study the microbial composition of biopsies in inflammatory bowel diseases. Materials and Methods. From November 2019 to February 2023, 100 patients of the coloproctology department with inflammatory bowel diseases (IBD) were examined: 65 patients with ulcerative colitis and 35 patients with Crohn’s disease. A metagenomic analysis of biopsies (DNA sequencer Illumina, USA) obtained during endoscopic examination using a standard technique, with a bioiformatic data analysis, was performed. The diversity of microbiomes in the samples was assessed using the Fisher index.

Objective. To investigate spectrum and antimicrobial susceptibility of colonic microorganisms isolated from biopsy samples in patients with ulcerative colitis. Materials and Methods. A total of 34 patients with ulcerative colitis (19 to 75 years of age) treated in proctology unit (Surgery Clinic of Samara State Medical University) during the 2009–2010 were examined in this study. Results. A total of 70 gram-negative isolates were obtained, of which Enterobacteriaceae were the most predominant pathogens.