S. pneumoniae

Nasopharyngeal carriage of Streptococcus pneumoniae in children from day-care centers in Smolensk

Objective. To investigate a nasopharyngeal carriage and serotypes of S. pneumoniae in children aged 3 to 6 years from day-care centers in Smolensk. Materials and Methods. A total of 245 isolates of S. pneumoniae from 1027 nasopharyngeal swabs from healthy children attending day-care centers was tested. Identification of S. pneumoniae was performed according morphological, cultural and antigenic characteristics (Slidex pneumo-Kit, bioMeriеux, France), susceptibility to optohin and bile. Extraction of S.

Impact of the 10-valent pneumococcal conjugate vaccine on the incidence of respiratory and ENT diseases and antibiotic consumption in children under 5 years of age in Barnaul

Objective. To evaluate epidemiological efficacy of the 10-valent pneumococcal conjugated vaccine (PCV10) as assessed by the number of episodes of respiratory tract and ENT diseases and by the number of antibiotic courses prescribed for those diseases in children under 5 years of age in Barnaul. Materials and Methods. At the end of 2016, a total of 312 children under 60 months of age were enrolled into a retrospective cohort epidemiological study and divided into 2 cohorts (156 children each).

Epidemiology of S. pneumoniae serotypes in the Russian Federation

The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological …

Changes in antimicrobial resistance in clinical pediatric isolates of Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis in Middle Ural area

Objective. To reveal the prevalence of antimicrobial resistance of H. influenzae, S. pneumoniae, and M. catarrhalis clinical pediatric isolates in Yekaterinburg and Sverdlovsk region during 2013-2015. Materials and Methods. In total 231 H. influenzae, 289 S. pneumoniae, and 266 M. catarrhalis isolates were included in the study. Antimicrobial susceptibility testing was performed partially by disc-diffusion method and partially by automated method, depending on the local practice; β-lacamase production was detected by the nitrocefin disc test.

Incidence of Community-Acquired Pneumonia and Acute Otitis Media in Children 0–5 Years in Russia and Role of S. pneumoniae or H. influenzae in the Etiology of the Diseases

Objective. To estimate the incidence of communityacquired pneumonias and acute otitis media and the role of S. pneumoniae and H. influenzae in these infections in children under 5 years. Materials and Methods. Investigational program PAPIRUS (Prospective Assessment of Pneumococcal Infection in RUSsia), which included multi-center prospective epidemiological study estimating the incidence of community-acquired pneumonia (CAP) and the role of S. pneumoniae and H. influenzae in CAP and acute otitis media (AOM) in children 0-5 years of age in 3 Russian cities (Barnaul, Yekaterinburg and Murmansk) and the prospective multi-center observational cohort study evaluating the incidence of AOM in children under 5 years in the same cities had been performed during 12 months.

Serological Characteristics and Antimicrobial Susceptibility of Streptococcus pneumoniae Isolated from Children Under 5 Years and Patients >65 Years in Belarus and Ukraine

Objective. Objectives. To reveal serotypes of Streptococcus pneumoniaе isolated from patients with pneumococcal infections and from healthy carriers in Belarus and Ukraine. Materials and Methods. There were 314 strains of S. pneumoniae in this investigation, from patients and asymptomatic carriers at the age from 0 to 90 years. After re-identification and susceptibility testing to penicillin, serogroup and serotype was identified for each strain. Using this data the coverage of 7-, 10- and 13-vallent pneumococcal conjugate vaccines was determined.

Review of Current Guidelines on the Management of Pediatric Patients with Acute Bacterial Rhinosinusitis

Acute bacterial rhinosinusitis (ABRS) is a common disease in pediatric practice, which takes a fifth place among the causes of antimicrobials administration to children. This paper presents a review of current clinical guidelines on the management of …

The Etiology of Acute Bacterial Sinusitis. Results of SSSR Multicenter Microbiological Study

Materials and Methods. The aim of the study was to determine the structure of bacterial pathogens and their antimicrobial resistance in adult patients with acute maxillary sinusitis. A total of 311 strains isolated from 442 adult patients with acute maxillary sinusitis were included in the study during 2000–2003. Results. Clinically significant bacterial pathogens were isolated in 65.4% of patients; among them single microorganism were found in 87.3% of cases, >2 – in 12.

Acute Bacterial Rhinosinusitis: Current Approaches to the Diagnostic and Antibacterial Therapy in Outpatient Settings

Acute rhinosinusitis is one of the most common disorders in otolaryngology and is on 5th place among all diseases based on the amount of all prescribed antimicrobials. But a number of problems in the antimicrobial therapy of this pathology still …