Experience in implementing the AMRcloud online platform for local antimicrobial resistance surveillance in a tertiary care hospital

Clinical Microbiology and Antimicrobial Chemotherapy. 2022; 24(1):39-46

​ Petrova L.V., Kuzmenkov A.Yu., Kamyshova D.A., Vinogradova A.G., Gusarov V. G., Zamyatin M.N.
10.36488/cmac.2022.1.39-46
AMRcloud antimicrobial resistance surveillance data analysis antimicrobial stewardship online platform
Section
Antimicrobial Resistance
Type
Original Article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2022; 24(1):39-46

Objective.

To create local antibiotic resistance surveillance system using the AMRcloud online platform to provide evidence base for activity of antimicrobials (AM) and antimicrobial resistance (AMR) epidemiology.

Materials and Methods.

This study was conducted at the Pirogov National Medical and Surgical Center (Moscow, Russia). The study is prospective, with two evaluations of the local AMR surveillance system (before and after the implementation of the AMRcloud online platform). Separately, the effects of implementing the AMRcloud platform were evaluated and the most frequent scenarios of using this system in hospital were studied.

Results.

With the help of the AMRcloud platform, which acts as one of the central links in the AMR surveillance process, a local AMR surveillance system was formed, providing continuity of historical data and evidence base on local AMR epidemiology with real-time access and bringing together specialists of various profiles.

Conclusions.

Implementation of the AMRcloud online platform into multidisciplinary hospital operations enables the creation of a local evidence base on AM activity and AMR epidemiology, as well as reducing the labor costs of several crucial stages of AMR surveillance – data storage, analysis and exchange.

Petrova L.V.

Pirogov National Medical and Surgical Center, Moscow, Russia

Kuzmenkov Alexey Yuryevich

Institute of Antimicrobial Chemotherapy, Smolensk, Russia

Kamyshova D.A.

Pirogov National Medical and Surgical Center, Moscow, Russia

Alina G. Vinogradova

Institute of Antimicrobial Chemotherapy, Smolensk, Russia

Vitaly G. Gusarov

Pirogov National Medical and Surgical Center, Moscow, Russia

Zamyatin M.N.

Pirogov National Medical and Surgical Center, Moscow, Russia

  • 1. O’Neill J. Antimicrobial resistance: tackling a crisis for the health and wealth of nations. Rev Antimicrob Resist. 2014;(December):1-16.
  • 2. Tacconelli E., Pezzani M.D. Public health burden of antimicrobial resistance in Europe. Lancet Infect Dis. 2019;19(1):4-6. DOI: 10.1016/S14733099(18)30648-0
  • 3. Tamma P.D., Avdic E., Keenan J.F., Zhao Y., Anand G., Cooper J., et al. What is the more effective antibiotic stewardship intervention: pre-prescription authorization or post-prescription review with feedback? Clin Infect Dis. 2017;64(5):537-543. DOI: 10.1093/cid/ciw780
  • 4. Barlam T.F., Cosgrove S.E., Abbo L.M., MacDougall C., Schuetz A.N., Septimus E.J., et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis. 2016;62(10):e51-e77. DOI: 10.1093/cid/ciw118
  • 5. Morency-Potvin P., Schwartz D.N., Weinstein R.A. Antimicrobial stewardship: how the microbiology laboratory can right the ship. Clin Microbiol Rev. 2017;30(1):381407. DOI: 10.1128/CMR.00066-16
  • 6. Yakovlev S.V., Briko N.I., Sidorenko S.V., Procenko S.V., Beloborodov V.B., Brusina E.B., et. al. SCAT (Strategy for the Control of Antimicrobial Therapy) Programme in Inpatient Care: Russian Clinical Guidelines. (Eds. Yakovlev S.V., Brico N.I., Sidorenko S.V., Protsenko D.N.). Moscow: Pero; 2018. 156 p. Russian.
  • 7. Karpov O.E., Gusarov V.G., Zamyatin M.N., Orlova O.A., Petrova L.V., Kamyshova D.A., et al. Management of antimicrobial resistance in a hospital: current state and future prospects. Kliniceskaa mikrobiologia i antimikrobnaa himioterapia. 2020;22(4):277-286. Russian. DOI: 10.36488/cmac.2020.4.277-286
  • 8. Kuzmenkov A.Y., Vinogradova A.G. Antimicrobial resistance monitoring: a review of information resources. Bull Sib Med. 2020;19(2):163-170. DOI: 10.20538/168203632020-2-163-170
  • 9. Pfizer. ATLAS: Antimicrobial Testing Leadership and Surveillance. https://atlas-surveillance.com. Published 2017. Accessed January 27, 2022.
  • 10. ECDC. Data from the ECDC Surveillance Atlas – Antimicrobial resistance. Available at: www.ecdc.europa.eu/en/antimicrobial-resistance/surveillance-and-diseasedata/data-ecdc. Published 2020. Accessed June 28, 2020.
  • 11. Public Health England. Second Generation Surveillance System (SGSS). Available at: https://sgss.phe.org.uk/Security/Register. Published 2014. Accessed January 27, 2022.
  • 12. CDDEP. Resistance Map. Antibiotic Resistance. Available at: https://resistancemap.cddep.org/AntibioticResistance.php. Published 2014. Accessed January 27, 2022.
  • 13. Vinogradova A.G., Kuzmenkov A.Y. Data handling as a basis for local antimicrobial resistance surveillance. Kliniceskaa mikrobiologia i antimikrobnaa himioterapia. 2020;22(2):137-141. Russian. DOI: 10.36488/cmac.2020.2.137-141
  • 14. Kuzmenkov A.Y., Vinogradova A.G., Trushin I.V., AvramenkoA.A., Edelstein M.V., Dekhnich A.V., et al. AMRcloud: a new paradigm in monitoring of antibiotic resistance. Kliniceskaa mikrobiologia i antimikrobnaa himioterapia. 2019;21(2):119-124. Russian. DOI: 10.36488/cmac.2019.2.119-124
  • 15. Kuzmenkov A.Y., Vinogradova A.G., Trushin I.V., Edelstein M.V., Avramenko A.A., Dekhnich A.V., et al. AMRmap – antibiotic resistance surveillance system in Russia. Kliniceskaa mikrobiologia i antimikrobnaa himioterapia. 2021;23(2):198-204. Russian. DOI: 10.36488/cmac.2021.2.198-204
  • 16. Edelstein M.V., Skleenova E.Y., Trushin I.V., Kuzmenkov A.Y., Martinovich A.А., Shek E.A., et al. Susceptibility of clinical Enterobacterales and Pseudomonas aeruginosa isolates to ceftazidime-avibactam in Russia: multicenter local laboratory databased surveillance. Kliniceskaa mikrobiologia i antimikrobnaa himioterapia. 2021;23(3):264-278. Russian. DOI: 10.36488/cmac.2021.3.264-278
Views
0 Abstract
0 PDF
0 Crossref citations
Shared