Oral third-generation cephalosporins in the treatment of community-acquired urinary tract infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(3):225-228

​ Kozlov R.S., Palagin I.S., Golub A.V.
10.36488/cmac.2019.3.225-228
urinary tract infections acute cystitis acute pyelonephritis cefixime cephalosporins
Section
Antimicrobials
Type
Review
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(3):225-228

Abstract

Cephalosporins are one of the most commonly used antimicrobials for the treatment of variety of bacterial infections. Prudent use of the third-generation cephalosporins is important for the control of spread of cephalosporin-resistant Gram-negative bacteria, especially ESBL-producing Enterobacterales strains. One of the therapeutic areas where the balance between the clinical efficacy and antimicrobial resistance is of critical importance for cephalosporins is urinary tract infections. Current review summarizes existing data on the use of oral third-generation cephalosporins in the treatment of urinary tract infections with a special emphasis to the microbiological data.

Roman S. Kozlov

Institute of Antimicrobial Chemotherapy, Smolensk, Russia

Ivan S. Palagin

Institute of Antimicrobial Chemotherapy, Smolensk, Russia

Alexey V. Golub

Institute of Antimicrobial Chemotherapy, Smolensk, Russia

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