Susceptibility to antiseptic preparations in biofilm-forming Staphylococcus aureus and Pseudomonas aeruginosa isolated from burn wounds

Clinical Microbiology and Antimicrobial Chemotherapy. 2018; 20(3):249-256

​ Andreeva S.V., Bakhareva L.I., Nokhrin D.Yu., Titova M.V., Khaidarshina N.E., Burmistrova A.L.
10.36488/cmac.2018.3.249-256
S aureus P aeruginosa burn wounds biofilm antiseptic resistance
Section
Personal Experience
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2018; 20(3):249-256

Abstract

The article presents data on susceptibility to antiseptic preparations in antibiotic-resistant S. aureus and P. aeruginosa strains isolated from burn wounds, which were tested in single-species and double-species biofilms with varying degrees (24-hour and 48-hour) of maturity. The studies demonstrated susceptibility of S. aureus and P. aeruginosa in single- and double-species biofilms to “Prontosan”, “Betadine” and “Chlorophyllipt” and resistance to “Miramistin” and “Chlorhexidine”. The bactericidal effect was achieved at concentrations 1.64 times higher than bacteriostatic concentrations for all the antiseptics tested. A double increase in antiseptic resistance level was observed over biofilm maturation process.

Svetlana V. Andreeva

Chelyabinsk State University, Chelyabinsk, Russia

Bakhareva L.I.

Chelyabinsk State University, Chelyabinsk, Russia
City Clinical Hospital #6, Chelyabinsk, Russia

Nokhrin D.Yu.

Chelyabinsk State University, Chelyabinsk, Russia

Titova M.V.

Chelyabinsk State University, Chelyabinsk, Russia

Khaidarshina N.E.

Chelyabinsk State University, Chelyabinsk, Russia

Burmistrova A.L.

Chelyabinsk State University, Chelyabinsk, Russia

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