Perioperative Antibacterial Support to Cataract Surgery

Clinical Microbiology and Antimicrobial Chemotherapy. 2016; 18(3):166-173

​ Fedyashev G.A., Eliseeva E.V.
cataract surgery antibacterial support endophthalmitis
Section
Diseases and Pathogens
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2016; 18(3):166-173

Abstract

This review contains information on the most common cause of infectious complications of early postoperative cataract surgery, and in particular endophthalmitis, its etiology, the role of the normal microflora in the development of infectious complications. In addition, the article describes the methods of antibacterial prophylaxis of endophthalmitis before surgery, during and after it. Besides the article compared the clinical effectiveness of the various methods for perioperative antibacterial support, based on the susceptibility of microorganisms to antimicrobials, the ability of drugs from various groups to penetrate and accumulate in eye tissues at different routes of administration.

Gleb A. Fedyashev

Pacific State Medical University, Vladivostok, Russia
Primorsky Center of Eye Microsurgery, Vladivostok, Russia

Ekaterina V. Eliseeva

Pacific State Medical University, Vladivostok, Russia

  • 1. Воронцова Т.Н., Бржеский В.В., М.В. Михайлова. Чувствительность и резистентность к антибактериальным препаратам микрофлоры конъюнктивальной полости у детей. Офтальмология 2012; 9(1):83-91.
  • 2. Рациональная антимикробная фармакотерапия. Руководство для практикующих врачей. Под ред. В.П. Яковлева, С.В. Яковлева. М.: «Литера», 2003. 1008 с.
  • 3. ESCRS guidelines for prevention and treatment of endophthalmitis following cataract surgery: data, dilemmas and conclusions 2013. Editors: Barry P., Cordovés L., Gardner S. ESCRS. 2013.
  • 4. Philip L.T.H., Young A.L., Cheng L.L., Tam P.M.K., Lee V.Y.W. Randomized controlled trial on the safety of intracameral cephalosporins in cataract surgery. Clin Ophthalmol 2010; 4:1499-504.
  • 5. Gentile R.C., Shukla S., Shah M., Ritterband D.C., Engelbert M, Davis A, Hu D.N. Microbiological spectrum and antibiotic sensitivity in endophthalmitis: a 25-year review. Ophthalmology 2014; 121(8):1634-42.
  • 6. Gower E.W., Keay L.J., Stare D.E., Arora P., Cassard S.D., Behrens A., Tielsch J.M., Schein O.D. Characteristics of endophthalmitis after cataract surgery in the United States medicare population. Ophthalmology 2015; 122(8):1625-32.
  • 7. Matsuura K., Mori T., Miyamoto T., Suto C., Saeki Y., Tanaka S., Kawamura H., Ohkubo S., Tanito M., Inoue Y. Survey of Japanese ophthalmic surgeons regarding perioperative disinfection and antibiotic prophylaxis in cataract surgery. Clin Ophthalmol 2014; 29(8):2013-8.
  • 8. Jindal A., Pathengay A., Jalali S., Mathai A., Pappuru R.R., Narayanan R., Chhablani J., Sharma S., Das T., Flynn H.W. Jr. Microbiologic spectrum and susceptibility of isolates in delayed post-cataract surgery endophthalmitis. Clin Ophthalmol 2015; 16(9):1077-9.
  • 9. Kompella U.B., Kadam R.S., Lee V.H.L. Recent advances in ophthalmic drug delivery. Ther Deliv 2010; 1(3):435-56.
  • 10. Moloney T.P., Park J. Microbiological isolates and antibiotic sensitivities in culture-proven endophthalmitis: a 15-year view. Br J Ophthalmol 2014; 98(11):1492-7.
  • 11. Hsu H.Y., Lind J.T., Tseng L., Miller D. Ocular flora and their antibiotic resistance patterns in the midwest: a prospective study of patients undergoing cataract surgery. Am J Ophthalmol 2013; 155:36-44.
  • 12. Porter L., Khan R.U., Hannan A., Kelly S.P. MRSA and cataract surgery – reflections for practice. Clin Ophthalmol 2010; 4:1223-7.
  • 13. Rodríguez-Caravaca G., García-Sáenz M.C., VillarDel-Campo M.C., Andrés-Alba Y., Arias-Puente A.J. Incidence of endophthalmitis and impact of prophylaxis with cefuroxime on cataract surgery. Cataract Refract Surg 2013; 39(9):1399-403.
  • 14. Бандурова Е.А., Шуматов В.Б., Елисеева Е.В. Локальный микробиологический мониторинг и антибиотикорезистентность основных патогенов у пациентов с хирургической патологией в отделении интенсивной терапии. Тихоокеанский медицинский журнал 2012: (2):25-9.
  • 15. Околов И.Н., Гурченок П.А. Резистентность к антибиотикам нормальной микрофлоры конъюнктивы пациентов перед офтальмохирургическими операциями. Офтальмологические ведомости 2008; 1(4):59-62.
  • 16. Сомов Е.Е., Воронцова Т.Н., Смолянинова Т.Н. Содержание антибиотиков в слезной жидкости и жидких средах глаза при различных способах их введения. Вестн офтальмол 1991; (4):56-9.
  • 17. Вохмяков A.B., Околов И.Н., Гурченок П.А. Выбор оптимального антибиотика для профилактики инфекционных осложнений в офтальмохирургии. Клиническая офтальмология 2007; 8(1):37-40.
  • 18. Сметанкин И.Г., И.Ю. Мазунин, Л.В. Коссовский, Профилактика и лечение гнойного эндофтальмита. Нижний Новгород: НижГМА, 2010. – С. 5-18.
  • 19. Li B., Miño de Kaspar H., Haritoglou C., Kook D., Kampik A., Sheng M., Nentwich M.M. Comparison of 1-day versus 1-hour application of topical neomycin/ polymyxin-B before cataract surgery. J Cataract Refract Surg 2015; 41(4):724-31.
  • 20. Niyadurupola N., Astbury N. Endophthalmitis: controlling infection before and after cataract surgery. Community Eye Health 2008; 21(65):9-10.
  • 21. Storey P., Dollin M., Pitcher J. et al. The role of topical antibiotic prophylaxis to prevent endophthalmitis after intravitreal injection. Ophthalmology 2014:121(1):283-9.
  • 22. Suzuki T., Tanaka H., Toriyama K, Okamoto S., Urabe K., Hashida M., Shinkai Y., Ohashi Y. J. Prospective clinical evaluation of 1.5% levofloxacin ophthalmic solution in ophthalmic perioperative disinfection // Ocul Pharmacol Ther 2013;29(10):887-92.
  • 23. George J.M., Fiscella R., Blair M., Rodvold K., UlanskiL., Stokes J., Blair N., Pontiggia L. Aqueous and vitreous penetration of linezolid and levofloxacin after oral administration. J Ocul Pharmacol Ther 2010; 26(6):579-86.
  • 24. Ishida M., Kataoka T., Niwa K., Iwaki M., Zako M. J. Efficient penetration into aqueous humor by administration of oral and topical levofloxacin. Ocul Pharmacol Ther 2011; 27(3):247-50.
  • 25. Bremond-Gignac D., Chiambaretta F., Milazzo S. A European perspective on topical ophthalmic antibiotics: current and evolving options. Ophthalmol Eye Dis 2011; 3:29-43.
  • 26. Barreau G., Mounier M., Marin B., Adenis J.P., Robert P.Y. Intracameral cefuroxime injection at the end of cataract surgery to reduce the incidence of endophthalmitis: French study. J Cataract Refract Surg 2012; 38(8):1370-5.
  • 27. Richman J., Zolezio H., Tang-Liu D. Comparison of ofloxacin, gentamicin, and tobramycin concentrations in tears and in vitro MICs for 90% of test organisms. Antimicrobial Agents and Chemotherapy 1990; 34(8):1602-4.
  • 28. Cantor L.B., WuDunn D., Yung C.W., Valluri S., Catoira Y.P., Hoop J.S., Morgan L.S. Ocular penetration of levofloxacin, ofloxacin and ciprofloxacin in eyes with functioning filtering blebs: investigator masked, randomised clinical trial. Br J Ophthalmol 2008; 3:345-7.
  • 29. Chung J.L., Lim E.H., Song S.W., Kim B.Y., Lee J.H., Mah F.S., Seo K.Y. Comparative intraocular penetration of 4 fluoroquinolones after topical instillation. Cornea 2013; 2(7):1046-51.
  • 30. May W.N., Castro-Combs J., Kashiwabuchi R.T. et al. Sutured clear corneal incision: wound apposition and permeability to bacterial-sized particles. Cornea 2013; 32:319-25.
  • 31. Sakamoto H., Sakamoto M., Hata Y., Kubota T., Ishibashi T. Aqueous and vitreous penetration of levofloxacin after topical and/or oral administration. Eur J Ophthalmol 2007; 17(3):372-6.
  • 32. Kessel L., Flesner P., Andresen J., Erngaard D., Tendal B., Hjortdal J.. Antibiotic prevention of postcataract endophthalmitis: a systematic review and meta-analysis. Acta Ophthalmol 2015; 93(4):303-17.
  • 33. Jenkins C.D., Tuft S.J., Sheraidah G., et al. Comparative intraocular penetration of topical and injected cefuroxime. Br J Ophthalmol 1996; 80:685-8.
  • 34. Barry P. Adoption of intracameral antibiotic prophylaxis of endophthalmitis following cataract surgery: update on the ESCRS endophthalmitis Study. J Cataract Refract Surg 2014; 40(1):138-42.
  • 35. García-Sáenz M.C., Arias-Puente A., RodríguezCaravaca G., Bañuelos J.B. Effectiveness of intracameral cefuroxime in preventing endophthalmitis after cataract surgery Ten-year comparative study. J Cataract Refract Surg 2010; 36(2):203-7.
  • 36. Vaziri K., Schwartz S.G., Kishor K., Flynn H.W. Endophthalmitis: state of the art. Clin Ophthalmol 2015; 9:95-108.
  • 37. Kessner R., Golan S, Barak A. Changes in the etiology of endophthalmitis from 2003 to 2010 in a large tertiary medical center. Eur J Ophthalmol 2014; 24(6):918-24.
  • 38. Rudnisky C.J., Wan D., Weis E. Antibiotic choice for the prophylaxis of post-cataract extraction endophthalmitis. Ophthalmology 2014; 121(4):835-41.
Views
0 Abstract
0 PDF
0 Crossref citations
Shared