New Systemic Antimicrobials | CMAC

New Systemic Antimicrobials

Clinical Microbiology and Antimicrobial Chemotherapy. 2015; 17(4):272-285

​ Reshetko O.V., Yakimova Yu.N.
investigational drug development new antimicrobial agents
Section
Antimicrobials
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2015; 17(4):272-285

Abstract

Development of new antimicrobial agents is one of the main directions to combat the problem of antimicrobial resistance. The article is an overview of innovative antibiotics for systemic use that are under non-clinical and clinical development stages. When a number of those new agents are in fact representing the existing classes of antimicrobials (β-lactams, macrolides, tetracyclines, polypeptides), some drugs are of truly new classes with novel mechanisms of action (chaperone LolA, protein FtsZ inhibitors etc.).

Olga V. Reshetko

Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia

Yakimova Yu.N.

Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia

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