Basic Principles of the Local Treatment of Wounds and Wound Infection

Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(3):214-222

​ Privolnev V.V., Karakulina E.V.
wound wound infection wound healing debridement dressing antiseptic ointment
Section
Diseases and Pathogens
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(3):214-222

Abstract

Due to success in antimicrobial therapy of skin and soft tissue infections, current consensus guidelines give less attention to surgical aspects of wound and wound infection treatment. This paper presents evolution of approaches to treatment of wounds over the last decades, as well as alternative approach to determination of wound process phase and to choice of local treatments. Main factors contributing to delayed/poor wound healing and algorithm for determining those factors are also considered. Different types of surgical debridement and their advantages and disadvantages are discussed. Review of modern antiseptics, dressing, and the most common ointments used for the local treatment of wounds in Russia is provided. Some promising options that may be used in the management of patients with wounds are listed. Finally, several clinical examples demonstrate common errors in the wound treatment of wounds.

  • 1. Кузин М.И. Общие принципы лечения гнойных ран.: Метод, рекомендации. М.И. Кузии М., 1985. - 31 с.
  • 2. Горюнов С.В., Роашов Д.В., Бутивщенко И.А. Гнойная хирургия. Атлас. М.: Бином. – 2004. – 558 с.
  • 3. Pulgar S., Mehra M., Quintara A., et al. The epidemiology of hospitalized cases of skin and soft tissue infection in Europe. 18th ECCMID, 2008, Barselona, Spain, Abstr. P. 821.
  • 4. Krasner D. Wound care: how to use the Red-YellowBlack system. Am J Nursing 1995; 95(5):44-7.
  • 5. Eskes A.M., Gerbens L.A., van der Horst C.M., Vermeulen H., Ubbink D.T. Is the red-yellow-black scheme suitable to classify donor site wounds? An inter-observer analysis. Burns 2011; 37(5):822-6.
  • 6. Гостищев В.К. Инфекции в хирургии. Руководство для врачей. В.К. Гостищев ГЭОТАР-Медиа, 2007. 768 с.
  • 7. Минченко А.Н. Раны. Лечение и профилактика осложнений. А.Н. Минченко А.Н. СПб., 2003. 207 с.
  • 8. Doughty D., Sparks-Defriese B. Wound-healing physiology. In: Bryant R.A., Nix D.P. Acute & Chronic Wounds: Current Management Concepts. 3rd ed. St. Louis, MO: Mosby/Elsevier; 2007:56-81.
  • 9. Evans E. Nutritional assessment in chronic wound care. J Wound Ostomy Continence Nurs 2005; 32:317-20.
  • 10. Rolstadt B.S., Ovington L. Principles of wound management. In: Acute & Chronic Wounds: Current Management Concepts. 3rd ed. St. Louis, MO: Mosby/Elsevier; 2007: 391-425.
  • 11. Bailey & Love’s. Short Practice of Surgery. 25th Edition. 2008.
  • 12. Bolton L. Operational definition of moist wound healing. J Wound Ostomy Continence Nurs 2007; 34:23-9.
  • 13. Bryan J. Moist wound healing: a concept that changed our practice. J Wound Care 2004; 13:227-8.
  • 14. Steed D.L., Donohoe D., Webster M.W., Lindsley L. Effect of extensive debridement and treatment on the healing of diabetic foot ulcers. Diabetic Ulcer Study Group. J Am Coll Surg 1996; 183:61-4.
  • 15. Алексеев А.А. Хирургическая обработка гранулирующих ран у обожженных. А.А. Алексеев, О.А. Кудзоев, П.Н. Тютюма и др. Комбустиология на рубеже веков: Междунар. конгр. М., 2000. - С. 131 -2.
  • 16. Brown D.L., Kao W.W., Greenhalgh D.G. Apoptosis down-regulates inflammation under the advancing epithelial wound edge: delayed patterns in diabetes and improvement with topical growth factors. Surgery 1997; 121:372-80.
  • 17. Collier M. Wound bed preparation: theory to practice. Nurs Stand 2003; 17:45-52.
  • 18. Falanga V. Classifications for wound bed preparation and stimulation of chronic wounds. Wound Repair Regen 2000; 8:347-52.
  • 19. Falanga V. Introducing the concept of wound bed preparation. Int Forum Wound Care 2001; 16:1-4.
  • 20. Гуманенко Е.К. Практикум по военно-полевой хирургии. Е.К. Гуманенко. Фолиант, 2006. 312 с.
  • 21. Ennis W.J., Meneses P. Wound healing at the local level: the stunned wound. Ostomy Wound Manage 2000; 46(1A Suppl):39S-48S.
  • 22. Mulder G.D., Vande Berg J.S. Cellular senescence and matrix metalloproteinase activity in chronic wounds. Relevance to debridement and new technologies. J Am Podiatr Med Assoc 2002; 92:34-7.
  • 23. Абдуллин А.И. Применение комбинированных коллагеновых покрытий в комплексном лечении гнойных ран. Клиническая анатомия и экспериментальная хирургия. Оренбург, 2004 - Вып. 4. С. 139-45.
  • 24. Алексеев А.А. Лечение ожоговых ран с применением раневых покрытий «Биодеспол». А.А. Алексеев, М.Г. Крутиков, А.Э. Бобровников и др. Материалы междунар. конф. Под ред. В.Д. Федорова, А.А. Адамяна. -М., 2001.-С. 133-5.
  • 25. Токмакова А.Ю., Галстян Г.Р., Анциферов М.Б. Современные иммобилизационные материалы в лечении синдрома диабетической стопы. Сахарный диабет 2001; (2):29-31.
  • 26. Удовиченко О.В., Галстян Г.Р. Иммобилизирующая разгрузочная повязка (Total Contact Cast) в лечении трофических язв у больных сахарным диабетом. Сахарный диабет 2003; (4):29-34.
  • 27. Korhonen K., Hirn M., Niinikoski J. Hyperbaric oxygen in the treatment of Fournier’s gangrene. Eur J Surg 1998; 164:251-5.
  • 28. Espensen E.H., Nixon B.P., Lavery L.A., Armstrong D.G. Use of subatmospheric (VAC) therapy to improve bioengineered tissue grafting in diabetic foot wounds. J Am Podiatr Med Assoc 2002; 92:395-7.
  • 29. Silberstein J., Grabowski J., Parsons J.K. Use of a vacuum-assisted device for Fournier's gangrene: a new paradigm. Rev Urol 2008; 10:76-80.
Views
0 Abstract
0 PDF
0 Crossref citations
Shared