Ertapenem – a Newer Carbapenem | CMAC

Ertapenem – a Newer Carbapenem

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(1):40-55

Section
Type
Journal article

Abstract

The carbapenems are class of beta-lactam antibiotics with exceptionally wide spectrum of activity, beneficial pharmacokinetic parameters and low toxicity as well. Such agents as imipenem and meropenem have already been succesfully used for a long time in clinical practice for treatment of severe nosocomial infections. The ertapenem appeared in 2002 represent a new class of carbapenems. It has differences from precursors in antimicrobial spectrum, including activity against ESBL and AmpC-producing microorganisms, and improved pharmacokinetics with once daily dosing. This paper provides an overview of pharmacological, microbiological and clinical data on ertapenem.

Views
0 Abstract
0 PDF
0 Crossref citations
Shared