Pharmacoeconomics | CMAC

Pharmacoeconomics

Clinico-Economic Effectiveness of Ceftaroline Fosamil for the Treatment of Hospitalised Patients with Pneumococcal Community-Acquired Pneumonia from a Societal Perspective

Objective. Due to high activity against Streptococcus pneumoniae ceftaroline fosamil (CF) presents a good option for the treatment of adults with pneumococcal communityacquired pneumonia (PCAP) requiring parenteral antibacterial therapy. We aimed to assess cost-effectiveness of CF for the treatment of PCAP in a multi-field hospital in Russia from a societal perspective. Materials and Methods. Decision tree model based on the results of two 3rd phase clinical trials (FOCUS 1, FOCUS 2) was created to represent a standard approach to the management of hospitalised patients with PCAP and estimated outcomes including possible recurrence of infection, direct and delayed attributive mortality in case of initial therapy with CF 600 mg BID vs.

Cefixime vs Ciprofloxacin for Acute Uncomplicated Cystitis: Clinico-Economic Study

Objective. To evaluate clinico-economical effectiveness of short course of cefixime and ciprofloxacin in women with acute uncomplicated cystitis. Materials and Methods. A prospective randomized clinico-economic study of effectiveness of cefixime and ciprofloxacin in 104 patients with acute uncomplicated cystitis. Results. At visit 2 (day 8) microbiological cure rates were detected in 95.9%, 55.6% and 71.4% of patients from Group 1 (cefixime), Group 2-a (ciprofloxacin 250 mg BID) and Group 2-b (ciprofloxacin 500 mg BID), respectively.

Pharmacoeconomic Analysis of Micafungin (Mycamin®) Use in the Treatment of Patients with Invasive Candidiasis

It was the first-in-Russia clinical and economic expertise of the micafungin (Mycamin) use in the treatment of adult patients with invasive candidiasis in intensive care units (ICUs). Using simulation methods, a total cost considering treatment …

Clinical and Pharmacoeconomic Analysis of the Treatment of Invasive Candidiasis in Intensive Care Units

Invasive candidiasis is a third or fourth cause of sepsis in intensive care units (ICUs). Clinical and pharmacoeconomic study of treatment for invasive candidiasis was first performed using mathematical modeling in Russian economic environment. ICU …

Clinical and Economical Expediency of Posaconazole Comparing with Fluconazole and Itraconazole in Primary Prophylaxis of Systemic Mycoses in Severe Neutropenic Patients

For the first time in Russian economic conditions and with use of mathematic modeling, clinical-economic study of posaconazole in comparison with fluconazole/itraconazole for primary prophylaxis of invasive mycoses in patients with severe neutropenia …

Pharmacoeconomics of Chronic Pathologic Process

Pharmacoeconomic studies have become an integral part of evidence based medicine at nowadays. However, difficulties in standardization of pharmaeconomical analysis methods and problems with lifelong therapy of chronic pathologic processes …